Progression of breast cancer recurrence

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Skip to Content. For her, medicine is not just a profession but also a calling. She completed her residency training in Anatomic and Clinical Pathology at Duke University and is a board-certified fellow of the College of American Pathologists.

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Published 28 January Breast cancer recurrence following active treatment: determining its incidence in the NSW population. Public Health Res Pract.

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Coping with a breast cancer recurrence. When breast cancer has come back after treatment, known as recurrencepeople often ask what their prognosis or outlook is. If breast cancer has come back in the chest or breast area, in the skin near the original site or scar, or if it has been a long time since you first had treatment, then the cancer can often be successfully treated. Some breast cancer specialists believe that a local recurrence does not mean that the cancer is more likely to spread in the future.

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Most people diagnosed with breast cancer will never have a breast cancer recurrence return of breast cancer. However, everyone who has had breast cancer is at risk of recurrence. Talk with your health care provider about your risk of breast cancer recurrence and things that may lower your risk.

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Steady rates of recurrence in women with estrogen receptor-positive disease could influence decisions about long-term therapy. Even 20 years after a diagnosis, women with a type of breast cancer fueled by estrogen still face a substantial risk of cancer returning or spreading, according to a new analysis from an international team of investigators published in the New England Journal of Medicine. Standard treatment for estrogen receptor-positive, or ER-positive, breast cancer includes five years of the endocrine-based treatments tamoxifen or aromatase inhibitors, both of which are taken daily as a pill.

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A breast cancer recurrence, or "recurrent breast cancer," is cancer that has come back in the same or opposite breast or chest wall after a period of time when the cancer couldn't be detected. During surgery to remove an original diagnosis of breast cancer lumpectomy or mastectomythe surgeon removes all the cancer that can be seen and felt. But tests for cancer aren't sensitive enough to detect tiny groups of cancer cells that may be left over after surgery.

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The goal of treating early and locally advanced breast cancer is to remove the cancer and keep it from coming back breast cancer recurrence. Most people diagnosed with breast cancer will never have a breast cancer recurrence return of breast cancer. However, everyone who has had breast cancer is at risk of recurrence. The risk of recurrence varies greatly from person to person.

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The recurrent cancer might come back in the same place it first started, or it might come back somewhere else in the body. For instance, prostate cancer might come back in the area of the prostate gland even if the gland was removedor it might come back in the bones. It may be called recurrent prostate cancer.

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Little is known about the occurrence, timing and prognostic factors for first and also subsequent local LRregional RR or distant DM breast cancer recurrence. As current follow-up is still consensus-based, more information on the patterns and predictors of subsequent recurrences can inform more personalized follow-up decisions. Extended Cox regression was used to model the hazard of recurrence over ten years of follow-up for not only site-specific first, but also subsequent recurrences after LR or RR. The risk of first recurrence was highest during the second year post-diagnosis 3.


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